Rheumatoid arthritis is a systemic autoimmune disorder characterized by chronic destructive inflammation of joints. Risk factors: Female gender. Genetic predisposition: Clinical features: Symptoms: Insidious onset painful multiple symmetric joints (MCP joints, PIP joints of hand, wrist, ankle, knee, shoulder, hips, elbow). Initial pattern of joint involvement could be polyarticular (>5 […]
Internal Medicine
Syncope is a transient, self-limited loss of consciousness due to acute global impairment of cerebral blood flow. The onset is rapid, duration brief, and recovery spontaneous and complete. Other causes of transient loss of consciousness need to be distinguished from syncope which includes: A syncopal prodrome (presyncope) is common, although […]
Sarcoidosis is multisystem granulomatous disorder unknown etiology characterized by presence of non-caseating granuloma. Its etiology is unknown and associated with class II HLA genes. It is less seen in smoker. Clinical features: Cough, dyspnea on exertion, stridor. Sarcoidosis is considered with other DPLD, as most of the cases affect lungs […]
